Dr. Samia Bachmann

Research Interests

• Influence of the autonomic nervous system on lymphangiogenesis
• Innervation of prostate cancer

Education & Positions held

2014 – present
Ph.D. thesis with Prof. Michael Detmar, Institute of Pharmaceutical Sciences, Pharmacogenomics, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland

Member of the Cancer Biology Program, Life Science Graduate School Zurich

2014
Doctor of Veterinary Medicine (DVM), Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Switzerland. Thesis title: “Functional roles of DTX3L and ARTD9 in prostate cancer”

2013
Master thesis: “Role of the B-lymphoma and BAL-1-associated protein BBAP/DTX3L in cancer”, Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, Switzerland

2011 - 2013
Master of Veterinary Medicine, Vetsuisse Faculty, University of Zurich, Switzerland

2008 – 2011
Bachelor of Veterinary Medicine, Vetsuisse Faculty, University of Zurich, Switzerland

Publications

Bachmann, SB, Detmar M, Proulx ST. (2018) Visualization and Measurement of Lymphatic Function In Vivo. Methods Mol Biol. 1846:197-211. doi: 10.1007/978-1-4939-8712-2_13.

Roudnicky F, Yoon SY, Poghosyan S, Schwager S, Poyet C, Vella G, Bachmann SB, Karaman S, Shin JW, Otto VI, Detmar M. (2018) Alternative transcription of a shorter, non-antiangiogenic thrombospondin-2 variant in cancer-associated blood vessels. Oncogene. 37(19): 2573-2585. doi: 10.1038/s41388-018-0129-z.

Gousopoulos E, Proulx ST, Bachmann SB, Dieterich LC, Scholl J, Karaman S, Bianchi R, Detmar M. (2017) An important role of VEGF-C in promoting lymphedema development. J Invest Dermatol. 137(9):1995-2004 doi: 10.1016/j.jid.2017.04.033

Bianchi R, Russo E, Bachmann SB, Proulx ST, Sesartic M, Smaadahl N, Watson SP, Buckley ChD, Halin C, Detmar M. (2017) Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes. Arterioscler Thromb Vasc Biol. 37(1): 108-117. doi: 10.1161/ATVBAHA.116.308020

Gousopoulos E, Proulx ST, Bachmann SB, Scholl J, Dionyssiou D, Demiri E, Halin C, Dieterich LC, Detmar M. (2016) Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function. JCI Insight, 1(16): e89081.

Christiansen AJ, Dieterich LC, Ohs I, Bachmann SB, Bianchi R, Proulx ST, Hollmén M, Aebischer D,  Detmar M. (2016) Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation, Oncotarget, 7, 26.

Chong C, Scholkmann F, Bachmann SB, Luciani P, Leroux JC, Detmar M, Proulx ST. (2016) In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging, Scientific Reports, 6, 22930.

Bachmann SB, Frommel SC, Camicia R, Winkler HC, Santoro R, Hassa PO. (2014) DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells, Molecular Cancer, 13(1): 125

Camicia R, Bachmann SB, Winkler HC, Beer M, Tinguely M, Haralambieva E, Hassa PO. (2013) BAL1/ARTD9 represses the anti-proliferative and pro-apoptotic IFN-γ-STAT1-IRF1-53 axes in diffuse large B-cell lymphoma, Journal of Cell Science, 126 (9) 1969-80.