PhD Public Presentations
Upcoming Presentations
Andrei Shved
Design of Transition-Metal-Catalyzed C–H Carboxylation of Secondary Alcohols
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Ilija Čorić
June 18, 2025 | 11:00 | HCI G 374
Felix Fleckenstein
Modulating Cobalt-Carbon Bond Strengths in a Vitamin B12 Model Complex
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Jérôme Lacour
July 2, 2025 | 13:30 | HCI G 374
Archived Presentations
Maurice Biedermann
Isonitriles in Chemical Biology: From Bioorthogonal Reactions with Azomethine Imines to Oxazole Prodrugs
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Pablo Rivera-Fuentes
15.01.2025
Henry Lindner
Photochemistry and Base-Metal Catalysis: Development of Novel Methods for Alkene Functionalization
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl Gademann
29.01.2025
Hendrik L. Schmitt
Construction and Modification of (Hetero-)Cyclic Scaffolds: From Transition Metal Catalysis to Ring Expansion and Back
Supervisor: Prof. Bill Morandi
Co-examiner: Prof. Jérôme Waser
12.03.2015
Olivera Stepanović
Understanding Ligand Effects in Palladium Chemistry: from β-elimination to New Chlorocarbonylation Reactions
Supervisor: Prof. Bill Morandi
Co-examiner: Prof. Dmitry Katayev
19.03.2025
Jinling Wang
Synthesis of Labelled Small Molecules, Peptides, and Proteins for Imaging
Supervisor: Prof. Jeffrey W. Bode
Co-examiners: Prof. Roger Schibli, Prof. Martin Baumgartner
31.03.2025
Vera Wanka
Novel Chemoenzymatic Approaches for the Generation of Activity-Based Probes Targeting the Ubiquitin and SUMO Systems
Supervisor: Prof. Kathrin Lang
Co-examiner: Prof. Ed Tate
28.05.2025
Anna Konopka
Automated Synthesis of Protein Degraders for Drug Discovery
Supervisor: Prof. Jeffrey W. Bode
Co-examiners: Prof. Alessio Ciulli, Prof. Nathalie Grob
04.06.2025
Kateryna Tolmachova
UFM1 and URM1 pathway profiling with protein-derived activity probes
Supervisor: Prof. Jeffrey W. Bode
Co-examiners: Prof. Jacob Corn, Prof. Ashraf Brik
04.06.2025
Maurice Andrey
Mechanistic Insights and Improvements of the Nickel-Catalyzed Cyclopropanation
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Thomas R. Ward
11.06.2025
Lukas Benzenberg
Mass Spectrometric Studies on the Structure of Desolvated Biomolecular Ions
Supervisor: Prof. Renato Zenobi
Co-examiner: Prof. Steen Brøndsted Nielsen
11.06.2025
Moritz Fink
Photoswitchable RNase L Activators for RNA Degradation with Antiviral Effects and Aryl Azo Cyclopropenium Photoswitches
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl Gademann
11.06.2025
Lukas Lüthy
Secondary Metabolites from Streptococcus Mutans: Synthesis and Study of the Mutanofactin and Mutanolin Families of Natural Products
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof Karl Gademann
11.06.2025
Toshiki Mikami
Orthogonal Lysine Protecting Groups for Chemoenzymatic Synthesis of Ubiquitin Chain
Supervisor: Prof. Jeffrey W. Bode
Co-examiners: Prof. Yohei Yamauchi, Prof. Gosuke Hayashi
11.06.2025
Collagen Model Peptides: From Fundamental Investigations to Biological Applications
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Pablo Rivera-Fuentes
24.01.2024
Heterobimetallic Complexes as Probes for Investigating Metal-Metal Interactions in Cross-Coupling Reactions
Supervisor: Prof. Peter Chen
Co-examiners: Prof. Hansjörg Grützmacher, Prof. Ilija Čorić
31.01.2024
Mass Spectrometry Advancements for Diverse Structural Biology Applications
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Paola Picotti, Prof. Timothy P. Jenkins
31.01.2024
Metabolism Beyond Borders: Periplasmic Shikimate Pathway Enzymes in Pathogenic Bacteria
Supervisor: Prof. Peter Kast
Co-examiners: Prof. Hubert Hilbi, Prof. Emma Slack
07.02.2024
Study of Non-Covalent Interactions in Onium Ions
Supervisor: Prof. Peter Chen
Co-examiners: Prof. Philippe Hünenberger, Prof. Reinhard Neier
10.04.2024
Selective Carbon–Phosphorus Bond Activation Strategies for Reaction Design
Supervisor: Prof. Bill Morandi
Co-examiner: Prof. Jérôme Waser
17.04.2024
New Frontiers in Nickel Chemistry: Well-Defined Nickel(I) Complexes and Mechanistic Studies of Functional Group Metathesis
Supervisor: Prof. Bill Morandi
Co-examiner: Prof. Eva Hevia
08.05.2024
Optimising Enzyme Function: Leveraging Classical and Ultrahigh-Throughput Screening
Supervisor: Prof. Helma Wennemers
Co-examiners: Prof. Donald Hilvert, Prof. Alexandria Deliz Liang
15.05.2024
Expanding the Bioorthogonal Chemistry Toolbox for Protein Labeling
Supervisor: Prof. Kathrin Lang
Co-examiner: Prof. Stephan Hacker
22.05.2024
Improving On-Line Breath Analysis with Ambient Mass Spectrometry
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Dirk Mohr, Prof. Pablo Sinues
22.05.2024
Total Synthesis of (+)-Aberrarone and Advances in Photoredox Chemistry – Exploring New Catalytic Systems in the Service of Synthesis
Supervisor: Prof. Erick M. Carreira
Co-examiners: Prof. Karl Gademann, Prof. Bill Morandi
05.06.2024
Cannabinoid Receptor 2 in the Spotlight: Ligand-Directed Covalent Probes and Rational Tailoring of Ligand Functionality
Supervisor: Prof. Erick M. Carreira
Co-examiners: Prof. James Frank, Dr. Uwe Grether
05.06.2024
Mechanistically Guided Predictive Modeling of Stoichiometric Elimination Reactions of Palladium (II) Complexes
Supervisor: Prof. Bill Morandi
Co-examiners: Prof. Peter Chen, Prof. Matt Sigman
21.08.2024
Charge-Tagged Cyclopentadienone Iron Complexes: Mechanistic Studies Using Mass Spectrometry for Catalytic Hydrogenation Reactions
Supervisor: Prof. Peter Chen
Co-examiners: Prof. Victor Mougel, Prof. Martin Albrecht
21.08.2024
High-throughput Synthesis of Chemical Libraries and Prediction of Reaction Outcomes
Supervisor: Prof. Jeffrey Bode
Co-examiners: Prof. Sereina Riniker, Prof. Philippe Schwaller
21.08.2024
Total Synthesis and Related Studies of Mutanobactins from the Human Oral Microbiome and Photochemical Rearrangements Towards the Synthesis of a Sesterterpene
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl Gademann
04.09.2024
Exploring Tigliane and Limonoid Natural Products: Total Synthesis of (+)-Pedrolide and Synthetic Studies on Andhraxylocarpin E
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl Gademann
18.09.2024
GR PROTAC and Beyond – Expanding the Toolbox for Targeting the Glucocorticoid Receptor
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Dennis Gillingham
15.09.2024
Stereoselective Organocatalytic Conjugate Addition Reactions to β-Nitroacrylates, Vinyl Triflones, and Oxetane-Containing Michael Acceptors: From Reaction Development to Synthetic Applications
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Christof Sparr
04.12.2024
Exploring new Ligand Scaffolds, well-defined Ru⁰-Precursors and the Scope of Rh-catalyzed Ketone Metathesis
Supervisor: Prof. Bill Morandi
Co-examiner: Prof. Eva Hevia
04.12.2024
Total Synthesis of Neocaesalpin A and Ruthenium-Catalyzed Asymmetric Allylic Substitution
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl Gademann
17.12.2024
Stereocontrol by Atropisomerism: Total Synthesis of (+)-Euphorikanin A and Development of Bivalent Ligands for Targeting GPCR Heterodimers
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl Gademann
17.12.2024
Potassium Acyltrifluoroborates (KATs) for Chemical Protein Synthesis and Modifications
Supervisor: Prof. Jeffrey Bode
Co-examiners: Prof. Kathrin Lang, Prof. Christian F. W. Becker
18.12.2024
Deliberate Design of Electrophiles for Catalytic Applications
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Jeffrey Bode
25.01.2023
Palladium-Catalysed Carbofunctionalisation Reactions of Acid Chlorides
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Helma Wennemers
01.03.2023
Initiation and Deactivation of Homogeneous Rhenium Olefin Metathesis Catalysts
Examiner: Prof. Peter Chen
Co-examiner: Prof. Christophe Copéret
15.03.2023
Synthetic Collagen Heterotrimers: Self-sorting, Functionalization and Higher-order Supramolecular Assembly
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Renato Zenobi
05.04.2023
Mass Spectrometric Methods for Studying Thermodynamic Properties of Biomolecular Systems
Examiner: Prof. Renato Zenobi
Co-examiner: Prof. Jonathan Hall
05.04.2023
Developments in Nickel-catalyzed Transfer Hydrocyanation Reactions and Novel Skeletal Editing Strategies through Nitrogen Atom Insertion
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Erick Carreira
12.04.2023
Rhodium-Catalyzed -Carbon Elimination from Unstrained Alcohols as a Strategy for Reversible Carbon-Carbon Bond Activation
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Peter Chen
26.04.2023
KAT Ligation with Quinolinium Acyltrifluoroborates (QATs) for Bioconjugations
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Roger Schibli
03.05.2023 Zoom
Methods Development, Structure Elucidation and Quantum-Mechanical Calculations: Harnessing Nickel and Iron for Strong Bond Functionalization
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Máté Bezdek
10.05.2023
The Rearranged Ingenane Diterpenoid (+)-Euphorikanin A: Enantioselective Total Synthesis and Chemical Insights into the Biosynthesis
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
17.05.2023
Towards Nanoscale Chemical Imaging of Biological Membrane using Tip-Enhanced Raman Spectroscopy
Examiner: Prof. Zenobi
Co-examiner Prof. Lippert
31.05.2023
Automated Chemical Systems and the Synthesis of Human Nerve Growth Factor
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Gisbert Schneider
05.07.2023
I. Toward the Total Syntheses of Ganoboninketals A-F
II. Organophotocatalytic Functionalization of Olefins
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
23.08.2023
Exploring the Uncharted Chemical Space of Polybenzenoid Hydrocarbons
Examiner: Prof. Peter Chen
Co-examiner: Prof. Renana Gershoni-Poranne, Prof. Kjell Jorner
23.08.2023
Unraveling London Dispersion in the Gas Phase
Examiner: Prof. Peter Chen
Co-examiner: Prof. Kjell Jorner
30.08.2023
Enzyme Engineering for Site-Specific Ubiquitylation
Examiner: Prof. Jeffrey Bode
Co-examiners: Prof. Kathrin Lang, Prof. Rebecca Buller
13.09.2023
Low-temperature Plasma Chemistry for Mass Spectrometry and Beyond
Examiner: Prof. Renato Zenobi
Co-examiner: Prof. Detlef Günther
06.12.2023
Taming Reactive Nitrogen Intermediates for Amination and Deaminative Coupling Reactions
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Erick Carreira
13.12.2023
Exploring the Cellular Black Box: From Small Molecule Synthesis of Transcription Factor Modulators to Biological Functions
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Michael Ristow
02.02.2022 Zoom
Gas-Phase Bond Dissociation Energies: Reconciling Theory with Experiment
Examiner: Prof. Peter Chen
Co-examiner: Prof. Jeremy Richardson
16.02.2022
Engineering Nonviral Protein Cages for Delivery Applications
Examiner: Prof. Peter Kast
Co-examiner: Prof. Donald Hilvert
16.03.2022 Zoom
Development of AFM-based Tip-Enhanced Raman Spectroscopy: Methodology and Applications
Examiner: Prof. Renato Zenobi
Co-examiner: Prof. Thomas Lippert
16.03.2022
Stereoselective Peptide Catalysis: From Synthesis of C-Substituted Succinimides to Kinetic Resolution of Chiral Aldehydes
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Erick M. Carreira
06.04.2022
Mass Spectrometric and Fluorescence Spectroscopic Studies on Ion Formation and (Bio-)molecular
Conformations in the Gas Phase
Examiner: Prof. Renato Zenobi
Co-examiners: Prof. Kathrin Lang, Prof. Ben Schuler
06.04.2022
C(sp2)–H Activation Beyond Arenes: Palladium-Catalyzed C–H Functionalization of Alkenes and Allenes
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
04.05.2022
Cytokine Engineering with Chemical Synthesis
Examiner: Prof. Jeffrey Bode
Co-examiners: Prof. Cornelia Halin Winter, Prof. Onur Boyman
11.05.2022 Zoom
Synthesis and Reactions of Potassium Acyltrifluoroborates (KATs) and Trifluoroborate Iminiums (TIMs)
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Maté J. Bezdek
11.05.2022 Zoom
Functionalization of Peptide-Stabilized Metal Nanoparticles and Quantum Dots – Towards Biomedical Applications
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Kathrin Lang
08.06.2022
Halogenated Thioesters in Organocatalysis and Borylated Prolines for Carbohydrate Recognition
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Bill Morandi
22.06.2022 Zoom
Tailored peptide catalysts for N-heterocyclic substituted substrates and cascade reactions
Examiner: Prof: Helma Wennemers
Co-examiner: Prof. Erick M. Carreira
22.06.2022
Synthesis of Saturated N-Heterocycles from Organostannanes
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Máté Bezdek
31.08.2022 Zoom
Synthetic and Semisynthetic Proteins as Probes for Ubiquitin-like Protein Pathways
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Jacob Corn
31.08.2022 Zoom
Direct Infusion Electrospray Ionization Mass Spectrometry for Rapid Analysis
Examiner: Prof. Zenobi
Co-examiner: Prof. Zamboni
14.09.2022
Customizing Nonribosomal Peptide Synthesis through Next-Generation Protein Engineering
Examiner: Prof. Jörn Piel
Co-examiner: Prof. Donald Hilvert
21.09.2022
Synthesis of N-Alkylhydroxylamine Triflic Acid Salts and their Application in Organic Synthesis
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Jeffrey Bode
28.09.2022
Direct Access to Unprotected Primary Amines via Iron Catalysis
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Jeffrey Bode
28.09.2022
Readily Accessible Cavitand Hosts for the Binding of Large Guests in Water: Towards the Development of Gd3N@C80 Complexes as Potential MRI Contrast Agents
Examiner: Prof. Peter Chen
Co-examiner: Prof. Helma Wennemers
28.09.2022
Harnessing Reversibility in Catalysis: Development of Novel Strategies for Halogenation and Functional Group Metathesis
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Máté Bezdek
12.10.2022
Carbon Nitrides in Single Atom Heterogeneous Catalysis and Metal-Free Photocatalysis
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
12.10.2022
Development and Application of Ambient Ionization Sources for Analyzing Metabolites in Single Cells
Examiner: Prof. Renato Zenobi
Co-examiner: Prof. Markus Stoffel
12.10.2022
Stereoselective Tripeptide Organocatalysis – Highly Reactive Electrophiles and Machine Learning
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Bill Morandi
02.11.2022
Non-invasive Metabolic Monitoring via Volatiles: in Humans, Bacteria and Mice
Examiner: Prof. Renato Zenobi
Co-examiner: Prof. Emma Wetter Slack
16.11.2022
Direct Mass Spectrometric Analysis of Exhaled Breath: Advances towards Clinical Application
Examiner: Prof. Renato Zenobi
Co-examiners: Prof. Emma Slack, Prof. Alexander Möller
14.12.2022
Potassium Acyltrifluoroborates (KATs) for Bio-Macromolecular Chemistry
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Athina Anastasaki
20.01.2021 Zoom
New Instruments and Techniques for Laser Spectroscopy of Mass-Selected Biomolecular Ions
Examiner: Prof. Renato Zenobi
Co-examiners: Prof. Roland Riek, Prof. Lars Konermann
17.03.2021 Zoom
Expanding the Nonribosomal Code with High-Throughput Protein Engineering
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Jörn Piel
14.04.2021 Zoom
From Imaging to Proteomics – Using Photoactivatable Probes to Study Enzymes
Examiners: Prof. Rivera-Fuentes, Prof. Bode
Co-examiner: Prof. Leroux
21.04.2021 Zoom
Dynamic Chemistry with Potassium Acyltrifluoroborates (KATs)
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Peter Chen
05.05.2021 Zoom
Out of the Dark, Into the Light: Fluorescent and Photoswitchable Probes for Cannabinoid Receptors
Examiner: Prof. Erick Carreira
Co-examiner: Prof. Helma Wennemers
26.05.2021 Zoom
Proline-Rich Peptides – From Molecular Receptors to Antimicrobial Agents
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Donald Hilvert
09.06.2021 Zoom
Total Synthesis and Biological Evaluation of Mutanobactin D from the Human Microbiome
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Helma Wennemers
16.06.2021 Zoom
Palladium-Catalyzed Cyclization Reactions
Examiner: Prof. Peter Chen
Co-examiner: Prof. Bill Morandi
16.06.2021 Zoom
Engineering Efficient Metalloenzymes from De Novo Protein Scaffolds by Directed Evolution
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Rudolf Glockshuber
30.06.2021 Zoom
Effect of the Linker of Radiolabeled Bombesin-based Peptides for Targeting the h-GRP Receptor
Examiner: Prof. Helma Wennemers
Co-examiners: Prof. Roger Schibli, Dr. Martin Béhé
28.07.2021 Zoom
Synthesis of Ubiquitin Chains by Chemical and Chemoenzymatic Conjugations
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Kathrin Lang
28.07.2021 Zoom
Development of Chemical Biology Tools to Modulate Redox Homeostasis and Study Subcellular Stress Responses
Examiner: Prof. Helma Wennemers
Co-examiners: Prof. Pablo Rivera-Fuentes, Prof. Karl-Heinz Altmann
18.09.2021 Zoom
When Shikimate Pathway Catalysts Team up: Chorismate Mutases and their Partner Enzymes
Examiner: Prof. Peter Kast
Co-examiner Prof. Jörn Piel
22.09.2021 Zoom
Noncovalent Interactions Studied by Chemical Crosslinking and High-mass MALDI Mass Spectrometry
Examiner: Prof. Renato Zenobi
Co-examiner: Prof. Gebhard Schertler
26.10.2021 Zoom
Engineering Peptides and Proteins for Affinity Chromatography and Biocatalysis
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Helma Wennemers
27.10.2021 Zoom
Ir-Catalyzed Enantioconvergent Synthesis of Protected Allenylic Amines, Synthesis of Methylated δ-Viniferin Derivatives, and Synthetic Studies on a Cassane Furanoditerpene
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
24.11.2021
Reversible Metathesis of Aryl Nitriles and Aryl Sulfides: A Stepping Stone Towards Organic Diversity
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Erick M. Carreira
24.11.2021 Zoom
Computational Design and Engineering of de novo Biocatalysts
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Kathrin Lang
01.12.2021 Zoom
The Power of Metal Catalysis: Asymmetric Allylic Substitution and Light-Mediated C–H Amination
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Antonio Togni
15.01.2020
Total Synthesis of (–)-Mitrephorone A
Examiner: Prof. Erick M. Carreira
Co-examiner: Prof. Karl-Heinz Altmann
25.03.2020 Zoom
Synthetic Collagen – From Conformational Design to Biological Applications
Examiner: Prof. Helma Wennemers
Co-examiner: Prof. Donald Hilvert
06.05.2020 Zoom
The Bioorthogonal Isonitrile–Chlorooxime Ligation
Examiner: Prof. Helma Wennemers
Co-Examiner: Prof. Jeffrey Bode
10.06.2020 Zoom
Mechanistic Investigations on Biologically Relevant Sulfur Systems
Examiner: Prof. Peter Chen
Co-examiner: Prof. Hansjörg Grützmacher
08.07.2020 Zoom
Synthesis of Saturated N-Heterocycles and α-Tertiary Amines
Examiner: Prof. Jeffrey Bode
Co-examiner: Prof. Bill Morandi
17.08.2020 Zoom
Protein Cages: Mimicry, Repurposing and Beyond
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Nenad Ban
30.09.2020 Zoom
New Amino Reagents for the Synthesis of Complex Saturated N-heterocycles
Examiner: Prof. Jeffrey Bode
Co-Examiner: Prof. Antonio Togni
07.10.2020 Zoom
Directed Evolution of Enzymes using Ultra-High Throughput Screening
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Andrew deMello
11.11.2020 Zoom
Mechanistic studies of heme proteins facilitated by enzyme engineering and genetic code expansion
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Bill Morand
24.11.2020
The Functional Group Metathesis of Aryl Iodides and Acid Chlorides: a Key for the Advent of Novel Carbofunctionalization Reactions via a Molecular Shuffling Process
Examiner: Prof. Bill Morandi
Co-examiner: Prof. Christophe Copéret
02.12.2020 Zoom
Synthesis of Water-Soluble C60, C70, and Gd3N@C80 Derivatives for Biological Applications
Examiner: Prof. Yoko Yamakoshi
Co-examiners: Prof. Carlo Thilgen, Prof. Victor Mougel
02.12.2020 Zoom
Divergent Evolution of an Artificial Carboligase
Examiner: Prof. Donald Hilvert
Co-examiner: Prof. Helma Wennemers
02.12.2020 Zoom
Lysine Acylation using Conjugating Enzymes for the Modification of Recombinant Proteins
Examiner: Prof. Jeffrey Bode
Co-Examiner: Prof. Donald Hilvert
09.12.2020 Zoom
Dispersion Effects on Stereoselectivity-Study of Asymmetric Epoxidation and Sulfoxidation
Examiner: Prof. Peter Chen
Co-examiner: Prof. Bill Morandi
16.12.2020 Zoom
Metabolic Insights Related to Sleep and Circadian Clocks from Mass Spectrometry-Based Analysis of Blood and Breath
Examiner: Prof. Renato Zenobi
Co-Examiners: Prof. Steven A. Brown, Prof. Emma Wetter Slack
16.12.2020 Zoom
Functional Nanomaterials for DNA Fabrication and Hierarchical Supramolecular Assembly
Examiner: Prof. Yoko Yamakoshi
Co-examiners: Prof. Nicholas Spencer, Prof. Chih-Jen Shih
16.12.2020 Zoom
Total Synthesis and Configurational Assignment of (–)-Merochlorin A and Au(I)-Catalyzed Cyclization of 1,3-Enyne Aldehydes
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl-Heinz Altmann
09.01.2019
Total Synthesis of (+)-Dendrowardol C and Investigation of Anti-Inflammatory Epoxyisoprostanes and their Analogs
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Helma Wennemers
16.01.2019
Iridium-Catalyzed Asymmetric Allylic Substitution with Enolate Surrogates and Enantioselective Addition of Alkynes to α,α-Dichlorinated Aldehydes
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
30.01.2019
Synthesis of New KAHA Ligation Monomers and Their Applications on Proteins
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Donald Hilvert
27.02.2019
On-line Breath Metabolomics with Ambient High-Resolution Mass Spectrometry
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Malcolm Kohler, Prof. Marloes Maathuis
22.05.2019
Capillary Gap Sampler: a microfluidic platform directly coupled to ESI-MS for rapid analysis of low sample amounts
Supervisor: Prof. Renato Zenobi
Co-examiner: Prof. Andrew deMello
29.05.2019
Proline-Rich Peptides – From Catalysts to Metal Organic Frameworks
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Erick M. Carreira
04.06.2019
Chemoselective Amide Bond-Forming Reactions with Acylboron Compounds
Supervisor: Prof. Jeffrey Bode
Co-examiner Prof. Helma Wennemers
05.06.2019
Chemical Methods to Tailor the Stability of Collagen Triple Helices
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Renato Zenobi
12.06.2019
Harnessing Plasma for Soft Ionization Mass Spectrometry
Supervisor: Prof. Renato Zenobi
Co-examiner: Prof. Detlef Günther
12.06.2019
On Photoinduced Transformations in Plasmonic Hot Spots
Supervisor: Prof. Renato Zenobi
Co-examiner: Prof. David Norris
12.06.2019
Nickel-Catalyzed Cyclopropanation with Lithiomethyltrimethylammonium Triflate
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Bill Morandi
26.06.20219
Synthetic Fermentation as a Platform for Library Synthesis, Drug Discovery, and Chemical Outreach
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Jonathan Hall
26.06.2019
Exploring the Potential of Shuttle Catalysis in Organic Synthesis
Supervisor: Prof. Bill Morandi
Co-examiner: Prof. Antonio Togni
26.06.2019
Coupling Surface Plasmon Resonance Imaging with MALDI Mass Spectrometry as a Screening Tool for Non-covalent Interaction Partners
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Jeffrey Bode, Prof. Andreas Plückthun
27.06.2019
Development of Photoactivatable Phosphines for the Induction of Reductive Stress and Peptides for Subcellular Targeting
Supervisor: Prof. Pablo Rivera-Fuentes
Co-examiner: Prof. Helma Wennemers
17.07.2019
London Dispersion in Molecular Systems
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Sereina Riniker
31.07.20219
Fundamental Reactions for Gold Catalysis
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Bill Morandi
02.10.2019
Synthesis of Potassium Acyltrifluoroborates with Transfer Reagents and their Applications to 3D Photopatterning of Hydrogels
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Bill Morandi
06.11.2019
Design of Functional Fluorophores for Single-Molecule Super-Resolution Microscopy and Live-Cell Tracking
Supervisor: Prof. Pablo Rivera-Fuentes
Co-examiner: Prof. Jeffrey Bode
13.11.2019
Total Synthesis of (+)-Shearinine D
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl-Heinz Altmann
20.11.2019
Gas-phase Study of Dispersion-bound Complexes
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Renato Zenobi
27.11.20219
Lipid Nanoparticles as MRI Contrast Agents for the Detection of Atherosclerotic Plaques
Supervisor: Prof. Yoko Yamakoshi
Co-examiners: Prof. Jean-Christophe Leroux, Prof. Peter Johann Walde
04.12.2019
Interfacial photochemical and catalytic reactions studied by tip-enhanced Raman spectroscopy
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Jeremy Richardson, Prof. A. Dieter Schlüter
04.12.2019
Total Synthesis and Structural Revision of a Harziane Diterpenoid
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Bill Morandi
11.12.2019
Towards the Synthesis of Javanicolide A and Ganoboninketal C
Supervisor: Prof. Erick M. Carriera
Co-examiner: Prof. Karl-Heinz Altmann
18.12.2019
Functional and Structural Studies of Bioactive Peptides: from Cell Penetration to Aggregation and Structure Stabilization
Supervisor: Prof. Donald Hilvert
Co-examiner: Prof. Helma Wennemers
18.12.2019
Nanoscale Imaging of 2D Materials by Tip-Enhanced Raman Spectroscopy
Supervisor: Prof. Renato Zenobi
Co-examiner: Prof. A. Dieter Schlüter
10.01.2018
Conformational Analysis of Peptides using RDC-enhanced NMR Spectroscopy
Supervisor: Prof. Helma Wennemers
Co-examiners: Prof. Roland Riek, Dr. Marc-Olivier Ebert
24.01.2018
Soft Ionization Mass Spectrometry: from Matrix-Assisted Laser Desorption/Ionization to Dielectric Barrier Discharge Ionization and Atmospheric Pressure Photoionization
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Andrew de Mello, Prof. Janusz Pawliszyn
31.01.2018
Exploring the Role of Halogens in Chlorosulfolipids
Supervisor: Prof. Erick M. Carriera
Co-examiner: Prof. Helma Wennemers
21.02.2018
Efforts Toward the Synthesis of Potassium Acyltrifluoroborates
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Antonio Togni
28.02.2018
From Structure to Function-Evolving De Novo Metalloenzymes
Supervisor: Prof. Donald Hilvert
Co-examiner: Prof. Jörn Piel
28.02.2018
Kinetic and Mechanistic Investigation of the Potassium Acyltrifluoroborate Ligation Reaction
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Simon M. Ametamey
07.03.2018
Lock 'em up: Putting Enzymes into Protein Cages
Supervisor: Prof. Donald Hilvert
Co-examiner: Prof. Helma Wennemers
07.03.2018
Total Synthesis of (−)-Rhazinilam and Related Alkaloids. Synthesis of Truncated Mutanobactin Analog
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl-Heinz Altmann
04.04.2018
Synthetic and Biological Investigation of Lipids from the Membrane of Ochromonas danica
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Donald Hilvert
11.04.2018
The Renaissance of Pentafulvene and Pentafulvene Chemistry
Supervisor: Prof. François Diederich
Co-examiner: Prof. Carlo Thilgen
25.04.2018
Molecular Recognition with Enantiopure Alleno-Acetylenic Cage Receptors
Supervisor: Prof. François Diederich
23.05.2018
Dissecting Non-covalent Interactions in Oligomeric Protein Complexes by Native Mass Spectrometry
Supervisor: Prof. Renato Zenobi
Co-examiner: Prof. François Diederich
23.05.2018
Peptide Catalyzed Conjugate Addition Reactions of Aldehydes to Nitroolefins - Mechanistic Insights and Transformation of Bifunctional
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Jeffrey Bode
06.06.2018
On the formation of ions
Supervisor: Prof. Renato Zenobi
Co-examiners: Prof. Detlef Günther, Dr. Jürgen Gross
06.06.2018
Fluorinated monothiomalonates in stereoselective organocatalysis
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Erick M. Carreira
04.07.2018
Total Synthesis of Epicolactone and Synthetic Studies on Mutanobactins A and C
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Karl-Heinz Altmann
11.07.2018
Investigating Noncovalent Interactions: Substituent Effects in Aromatic p–p Stacking and s-Hole Interactions in Supramolecular Capsules
Supervisor: Prof. François Diederich
Co-examiner: Prof. Pablo Rivera-Fuentes
25.07.2018
Total Synthesis of Sarcophytin and Studies Towards Pavidolide B and related Cembranoids
Supervisor: Prof. Erick M. Carreira
Co-examiner: Prof. Antonio Togni
05.09.2018
Enteroendocrine L cells and metabolic disease
Supervisor: Prof. E. Carreira
Co-examiners: Prof. M. Stoffel, Prof. Ch. Wolfrum, Dr. S. Wolfrum
19.09.2018
Chemical Synthesis of Insulin Variants by KAHA Ligation
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Dario Neri
26.09.2018
Building Block Approaches to the Synthesis of Lasso Peptides and Polycyclic Saturated N-Heterocycles
Supervisor: Prof. Jeffrey Bode
Co-examiner: Prof. Peter Chen
26.09.2018
Infrared Ion Spectroscopy in a Cold FT-ICR Cell
Supervisor: Prof. Peter Chen
Co-examiner: Prof. Renato Zenobi
03.10.2018
The Self-Assembly of Oligoproline-Chromophore Conjugates
Supervisor: Prof. Helma Wennemers
Co-examiner: Prof. Pablo Rivera-Fuentes
03.10.2018
Structure-Based Design of Cyclohexylpyrrolidine-Based Ligands for Trypanothione Reductase: A Potential Target for Neglected Tropical Diseases
Supervisor: Prof. Carlo Thilgen
Co-examiners: Prof. François Diederich, Prof. Donald Hilvert
14.11.2018
Helicene Dimers and Oligomers: Novel Chiral Chromo- and Fluorophoric Materials
Supervisor: Prof. Carlo Thilgen
Co-examiners: Prof. François Diederich, Prof. Dieter Schlüter
21.11.2018
Improving enzymes by ultrahigh-throughput directed evolution and genetic code expansion
Supervisor: Prof. Donald Hilvert
Co-examiner: Prof. Helma Wennemers
19.12.2018
Sean Oriana
Design and Synthesis of Macromolecular Imaging Probe and Photodynamic Therapy Photosensitizer
Supervisor: Prof. Dr. Y. Yamakoshi
Co-examiner: Prof. Dr. J.-C. Leroux
11.01.2017
Michael Umberto Lüscher
SnAP Reagents for the Preparation of Functionalized, Saturated N-Heterocycles
Supervisor: Prof. Dr. J.W. Bode
Co-examiner: Prof. Dr. J. Hall
08.03.2017
Bernd Wolfstädter
Small Molecule Receptors Involved in the Metabolic Syndrome
Supervisor: Prof. Dr. E. M. Carreira
Co-examiners: Prof. Dr. C. Wolfrum, Dr. S. Wolfrum
09.03.2017
Claudia Elena Murar
Chemical Synthesis of Betatrophin, Interleukin-2 and Protein Aldehydes by α-Ketoacid-Hydroxylamine (KAHA) Ligation
Supervisor: Prof. Dr. J. W. Bode
Co-examiner: Prof. Dr. D. Neri
15.03.2017
Oliver Engl
Stereoselective Addition Reactions of Thioester Enolate Surrogates under Mild Organocatalytic Conditions
Supervisor: Prof. Dr. H. Wennemers
Co-examiner: Prof. Dr. E.M. Carreira
12.04.2017
Thibault Harmand
Chemical Synthesis of Betatrophin and the Integral Membrane Protein IFITM3 by KAHA Ligation
Supervisor: Prof. Dr. J. W. Bode
Co-examiner: Prof. Dr. D. Hilvert
19.04.2017
Carlotta Foletti
Short Proline-Rich Peptides as Molecular Receptors
Supervisor: Prof. Dr. H. Wennemers
Co-examiner: Prof. Dr. D. Hilvert
25.04.2017
Florian Nicolas Rohrbacher
Synthesis of Cyclic Peptides and Proteins by α-Ketoacid-Hydroxylamine Ligation
Supervisor: Prof. Dr. J. W. Bode
Co-examiner: Prof. Dr. J. Piel
10.05.2017
Lukas Bregy
Development and Application of Ambient Mass Spectrometry for Diagnosis of Respiratory and Dental Diseases
Supervisor: Prof. Dr. R. Zenobi
Co-examiners: Prof. Dr. M. Detmar, Prof. Dr. M. Kohler
17.05.2017
Stefano Corra
Peptides as Scaffolds for the Controlled Formation of Nanostructures
Supervisor: Prof. Dr. H. Wennemers
Co-examiner: Prof. Dr. A.D. Schlüter
14.06.2017
Johannes Boshkow
Investigating the Chemistry and Biology of Danicalipin A and its Analogs
Supervisor: Prof. Dr. E. M. Carreira
Co-examiner: Prof. Dr. A. Togni
21.06.2017
Elisabeth Schäfer
Design and Synthesis of Carbohydrate-Based lin-Benzoguanines as Inhibitors of tRNA-Guanine Transglycosylase
Supervisor: Prof. Dr. F. Diederich
Co-examiner: Prof. Dr. P. Kast
12.07.2017
Stefanie Dobitz
Oligoprolines as Multivalent Scaffolds for Tumor Targeting
Supervisor: Prof. Dr. H. Wennemers
Co-examiner: Prof. Dr. P. Rivera-Fuentes
19.07.2017
Jovanna Milic
Photoredux-Switchable Molecular Grippers: Design, Synthesis, and Spectroscopic Investigation
Supervisor: Prof. Dr. F. Diederich
Co-examiners: Prof. Dr. Y. Yamakoshi, Prof. Dr. O. Wenger
19.07.2017
Elisha Gabielle Tiu
Synthesis and Characterization of Fullerene and Metallofullerene Derivatives by Prato Reaction
Supervisor: Prof. Dr. Y. Yamakoshi
Co-examiner: Prof. Dr. C. Thilgen
19.07.2017
Mario Lenz
Control of Tetrathiafulvalene-gold Microstructure Formation in Microfluidic Poly (dimethylsiloxane) Devices and in situ Sensor Application
Supervisor: Prof. Dr. F. Diederich
Co-examiners: Prof. Dr. P. Dittrich, Prof. Dr. T. Lippert
09.08.2017
Matthias Valentin Westphal
Novel Chemical Probes for the Cannabinoid System
Supervisor: Prof. Dr. E. M. Carreira
Co-examiner: Prof. Dr. P. Rivera-Fuentes
09.08.2017
Raphael Joseph Oeschger
Development of Model Complexes for the Study of the Transmetalation Step in Palladium Catalyzed Cross-Coupling Reactions
Supervisor: Prof. Dr. P. Chen
Co-examiner: Prof. Dr. H. Grützmacher
30.08.2017
Anatol Otto Rudolf Georg Schwab
Allosteric Inhibitors of the Enzyme IspD of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis
Supervisor: Prof. Dr. F. Diederich
Co-examiner: Prof. Dr. G. Schneider
20.09.2017
Eirik Lyngvi
Selected Topics in Catalysis - Combining Computations and Experiments
Supervisor: Prof. Dr. P. Chen
Co-examiner: Prof. Dr. A. Togni
27.09.2017
Michael Andreas Schafroth
From Synthesis to Proteomics: Adventures in the Cannabis Field and at the Cell Surface
Supervisor: Prof. Dr. E. M. Carreira
Co-examiners: Prof. Dr. H. Wennemers, Prof. Dr. B. Wollscheid
25.10.2017
Agni Faviola Mika Gavriilidou
Native Mass Spectrometry in Drug Discovery and as a Structural Biology Tool
Supervisor: Prof. Dr. R. Zenobi
Co-examiner: Prof. Dr. G. Schertler
15.11.2017
Geoffrey Schwertz
Rational Design of Inhibitors for Serine Hydroxymethyltransferase: From Prospective Agrochemicals to Highly Efficient Antimalarials
Supervisor: Prof. Dr. F. Diederich
Co-examiner: Prof. Dr. D. Hilvert
22.11.2017
David Niquille
Reprogramming Nonribosomal Peptide Synthesis
Supervisor: Prof. Dr. D. Hilvert
Co-examiner: Prof. Dr. J. Piel
06.12.2017
Susanne Mailand
The Exported Chorismate Mutase from Bacterial Pathogens of Mammals: From Residues Important for Protein Export to the Quest for the Biological Function
Supervisor: Prof. Dr. P. Kast
Co-examiners: Prof. Dr. W.-D. Hardt, Prof. Dr. B. Bodenmiller
20.12.2017
Adrian Bunzel
De Novo Enzyme Engineering: Directed Evolution of Computationally Designed Enzymes
Supervisor: Prof. Dr. D. Hilvert
Co-examiner: Prof. Dr. H. Wennemers
20.12.2017