11

Protein-​like aggregates known as amyloids can bind to molecules of genetic material. It is possible that these two types of molecules stabilised each other during the development of life – and that this might even have paved the way for the genetic code.

A new AI model developed by researchers led by Gisbert Schneider can not only predict where a pharmaceutically active molecule can be chemically modified, but also how best to do it. This makes it possible to identify new pharmaceutical ingredients more quickly and improve existing ones in a targeted manner.

Researchers led by Professor Ursula Quitterer (IPW) have now shown that a previously unknown protein plays a key role in a congenital malformation of the heart. Their findings point the way towards new treatment options.         

Professor Helma Wennemers has been teaching at D-CHAB for twelve years with unwavering enthusiasm – be it specialized lectures or introductory lectures in organic chemistry. For her performance, the ETH Zurich Student Association (VSETH) has honored her with the Golden Owl 2023. In this interview, she speaks about her experiences and role models and reveals the value of traditional teaching methods.

As natural catalysts, enzymes are highly efficient at speeding up complex chemical reactions. Victor Mougel and his team aim to mimic this ability. They are the first to synthesize a complete series of iron-sulfur cubane redox clusters with all oxidation states, revealing how the clusters’ environment affects redox potential and reactivity. They also proved the clusters' effectiveness in developing efficient CO₂ reduction catalysts. Mougel receives the Ruzicka Prize 2023 on Nov. 23.